Pickens, Andrew (1739–1817), a United States Revolutionary War army officer. Pickens was born near Paxtang, Pennsylvania. His family settled in South Carolina in 1752, and he became a farmer. Like Francis Marion and Thomas Sumter, Pickens led partisan bands against the British and Loyalists. For his part in the American victory in the Battle of Cowpens (1781) he was made a brigadier general of state militia. Pickens served in the U.S. House of Representatives, 1793–95. Between 1785 and 1801 he often represented the federal government in negotiations with Southern Indians.